If sleep changes began after starting, stopping, or changing a medication, that timeline is worth reviewing with a clinician or pharmacist
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Type B symptoms also include intellectual disability, lactic acidosis and ketoacidosis, as well as hyperammonemia
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In addition, folate is synthesized and stored as poly-gamma-glutamate forms in plant cells and can be hydrolyzed into mono-glutamic forms by the enzyme gamma-glutamyl hydrolase (GGH), which has an important influence on the cellular homeostasis of folate [1, 24, 28]
At the doses used, MB has caused significant hemolysis in children in Africa